Leptinal - The Leptin Helper for cardiovascular health and weight management – Wellness Resources
You've already reviewed this product from this device. Do you want to write another review?
Write another review
Not now
How would you rate this product?
We would love it if you would share a bit about your experience.
Leptinal®
Leptinal®
Review content (Required)
We'll only contact you about your review if necessary. By submitting your review, you agree to our terms and conditions and privacy policy.
About you
Please tell us more about you.
Email address (Required)
We respect your privacy.
Display name (Required)
This won't be visible to other customers.
Post review as anonymous
Share a picture
Upload a photo to support your review.
Click to upload or drag and drop
Back
Next
Thanks for your review!
We are processing it and it will appear on the store soon.
Please confirm your email by clicking the link we just sent you. This helps us keep reviews authentic.
Would you like to share your experience of shopping with us?
We value your feedback and use it to improve. Please share any thoughts or suggestions you have.
Close
Your Cart
Your cart is empty
Loading...
Estimated total
$0.00 USD
Taxes, Discounts and shipping calculated at checkout
[View Cart](/content/cart "View Cart"/index.html)
Check out
Search
SearchClear
Free Shipping on Subscriptions and $49+
25% off Daily Supplements in October!
Free Shipping on Subscriptions and $49+
25% off Daily Supplements in October!
Free Shipping on Subscriptions and $49+
1/8
Leptinal®
Heart Health & Weight Management Formula*
4.44 / 5.0
(9)9 total reviews
$55.00$44.00-20%
This powerful omega oil and antioxidant blend supports a healthy metabolism and cardiovascular wellness. Leptinal® enhances calorie burning and helps curb food cravings. Formulated with DHA fish oil, tocotrienol vitamin E, and potent antioxidants.*
Size: 90 capsules
90 capsulesVariant sold out or unavailable 180 capsulesVariant sold out or unavailable
Quantity
Quantity Decrease quantity for Leptinal®Increase quantity for Leptinal®
One-time purchase
$55.00
$44.00
Subscribe & Save
Save Extra 15%
$44.00
$37.40
Frequency
Deliver every 30 daysDeliver every 45 daysDeliver every 60 daysDeliver every 90 daysDeliver every 120 days
Subscription details
Unlock the benefits of Subscribe & Save! Add your favorite supplements to a regular subscription and get an extra 15% off and free U.S. shipping! Set your schedule, update or cancel anytime.
Add to cart
✓In Stock - Ships Same or Next Day
Earn up to 165 Points when completing this purchase.
- Free U.S. Shipping with Subscription or $49+
- 90-Day Happiness Guarantee
- Manufactured in USA & Third-Party Tested
Share:
Share on Facebook Share on X Pin on Pinterest
CopiedCopy link
How does Leptinal® support healthy metabolism?What cardiovascular wellness benefits does Leptinal® provide?Which ingredients support healthy cholesterol metabolism?How many capsules should I take per day?What nutrients are included in Leptinal®’s omega oil blend?
Supports metabolism, cardiovascular wellness, brain health, and eyes.*
- Key Benefits: Supports weight management and cardiovascular health*
- Enhances thyroid function and leptin hormone communication*
- Promotes healthy cholesterol metabolism and blood pressure function*
- Contributes to healthy bones and nerves*
How It Works
Leptinal® is our premier cardiovascular and weight management support supplement. It contains a potent array of heart-friendly nutrients, all in one softgel capsule. Formulated with mercury-free DHA in the TG form, a special pomegranate extract, borage oil, and a unique combination of citrus-polyflavones and tocotrienols.*
The Leptinal Quality Difference
- Premium Quality Fish Oil: Mercury-free omega-3 fish oil DHA, molecularly distilled to ensure purity without the risk of heavy metals or chemical residues.
- Natural Triglyceride (TG) Form: Fish oil that won't oxidize within the capsule, preserving its integrity and free from soy and rancid oils.
- Powerful Antioxidants: Includes standardized pomegranate extract and tocotrienols, the most potent form of vitamin E, to offer enhanced cardiovascular protection.*
- GLA from Borage Oil: High purity omega oil for arterial and blood pressure health.*
Weight Management
Leptinal® is designed to reduce metabolic stress from fat cells and support normal fat metabolism. DHA helps lower excess leptin production and activates signals to break down stored fat (UCP2). It also promotes a gene in muscles (UCP3) that helps burn fat for energy, especially during exercise.*
Punicalagins from pomegranate naturally regulate cellular stress, which is essential for healthy metabolism. The punicalagins of pomegranate are a nutritional tool the body may use to naturally regulate stressful cellular signals. Too much cellular stress interferes with metabolic signals needed for healthy metabolism.
Leptinal® is a synergistic combination of nutrients that work to improve the fitness of your fat cells and support weight management. Research shows a combination of DHA, nobiletin, and tangeretin support weight management by promoting healthier fat cells that store less fat and resist expansion. These nutrients also help fat cells produce adiponectin, a hormone vital for proper insulin function.*
Supporting Thyroid Function
Leptinal® supports thyroid function by helping to balance leptin. Proper leptin entry into the brain is essential for triggering thyroid hormone production, but high triglyceride levels can interfere with this process. Nutrients like DHA and citrus polyflavanoids in Leptinal® help promote healthy triglyceride levels, ensuring leptin can enter the brain properly.*
Thyroid hormone activation also occurs in the liver, where DHA, GLA, and tocotrienols strengthen cell membranes. This supports the normal activation of thyroid hormone, which works with DHA to activate genes that promote natural fat burning.*
Healthy Bones and Nerves
DHA accumulates in bones and is essential for their healthy structure and function. Tocotrienols support bone formation, making bone health important during any weight management program.*
Protecting brain cells is vital since they don’t regenerate like other cells. Alpha tocotrienol, a form of vitamin E, is easily absorbed into nerve cell membranes and acts as a powerful antioxidant. Animal studies suggest that pomegranate's antioxidants also protect the nervous system.*
Blood Pressure
DHA supports healthy arterial structure and flexibility, which enhances blood flow and heart function. GLA, another key component, helps build healthy cell membranes, including those in arteries.*
DHA and GLA also support the production of beneficial prostaglandins (PGE3 and PGE1) that help regulate blood pressure and circulation. Since these essential fatty acids are often lacking in the American diet, supplementation with Leptinal® is a convenient way to increase your intake.*
Our pomegranate extract, rich in punicalagins, provides powerful antioxidants that protect the cardiovascular system. Tocotrienols also support healthy circulation and the lining of blood vessels.*
Healthy Cholesterol Levels
Maintaining healthy cholesterol levels naturally is vital for cardiovascular health. This requires eating a balanced diet, limiting fat and sugar intake, and exercising regularly. Leptinal® complements a healthy lifestyle to help you maintain healthy cholesterol levels.*
Sytrinol™, with citrus compounds tangeretin and nobiletin, supports healthy LDL cholesterol levels by modulating the production of apo-B and triglycerides. Human clinical trials show Sytrinol™ helps maintain healthy cholesterol levels, including HDL. In softgels containing DHA and tocotrienols, Sytrinol™ is four times better absorbed than in a plain powder capsule.*
Leptinal® also includes tocotrienols from palm fruit and rice bran oil. Alpha tocotrienol is a strong antioxidant that protects circulation and nerves, while gamma tocotrienol helps maintain normal cholesterol levels.*
GLA and DHA in Leptinal® support the formation of HDL cholesterol and overall metabolism of cholesterol and triglycerides.*
The FDA allows the following claim: Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease.
The Power of Leptin
Leptin is a hormone produced mainly by fat cells in white adipose tissue. It travels through the blood to the brain, where it regulates key metabolic signals involved with energy production, cholesterol synthesis, thyroid function, liver and pancreatic function, and bone formation. Proper leptin function is crucial for effective weight management, as it ensures smooth communication between fat cells, the brain, liver, and pancreas.
Just like muscles can get out of shape, white adipose tissue can become less effective over time. Enlarged fat cells struggle to release stored fat and may start producing stress signals that complicate weight management. Disrupted leptin communication can lead to metabolic stress and weight management challenges.
The big question of the twenty-first century is: How fit is your fat? The Leptin Diet book explains how to eat to be in harmony with leptin, vital information for healthy weight management.*
Leptinal® offers a powerful blend of nutrients to improve leptin hormone communication with the brain.*
How To Take
Take 2 capsules, up to three times per day.
Leptinal
Directions:
Take 2 capsules, up to three times per day.
Supplement Facts
Serving Size:
2 softgel capsules
| Amount Per Serving | % Daily Value | |
|---|---|---|
| Calories | 15 | |
| Calories from fat | 15 | * |
| Total Fat | 1.5g | 2%** |
| Marine Lipid Oil (providing 500 mg DHA and 100 mg EPA) | 1000 mg | * |
| Borage Oil (providing 110 mg of GLA) | 550 mg | * |
| Pomegranate Extract ( Punica granatum L.) (fruit) (minimum 40% punicalagins) | 200 mg | * |
| Sytrinol® (a proprietary blend of citrus-derived polymethoxylated flavones and palm-derived tocotrienols) (fruit) | 100 mg | * |
| Tocotrienols (from Rice Oryza Oil) | 20 mg | * |
\\ Percent Daily Value based upon a 2,000 calorie diet. \* Daily Value not established
Other Ingredients:Rice oryza oil, beeswax, extra virgin olive oil. Softgel shell: gelatin, glycerin, purified water, carob.
This product does NOT contain: milk, egg, Crustacean shellfish, tree nuts, peanuts, wheat, gluten, soy, or sesame. This product does not contain hidden fillers, preservatives, sugar, artificial sweeteners, colors, or flavors.
Sytrinol® is a trademark of InterHealth N.I. Sytrinol® branded blend of citrus and palm fruit extracts (U.S. patents 6987125 and 7683095).Leptinal® is a registered trademark of Wellness Resources, Inc.
Manufactured in the USA
We source the highest quality, most absorbable nutrients. Our supplements are manufactured in the United States under stringent quality standards.
Third-Party Tested
Wellness Resources supplements are tested throughout production for potency and purity. Each final batch is tested to ensure you are getting what's on the label.
Family-Owned Since 1985
Our specialty formulas are backed by science and years of experience. Made with care, from our family to yours. A supplement line you can trust.
Customer Reviews
Write a review
Filters
Sort byMost RecentHighest RatingLowest RatingOnly PicturesPictures FirstVideos FirstMost Helpful
Summarized and selected by AI from recent customer reviews
Customers say
Customers praised this supplement for cardiovascular wellness and metabolism support. One long-term shopper reported normal blood pressure and no cardiac medications after 20 years of use. Benefits include reduced bloating and fat. However, one customer experienced an allergic reaction with itching.
A
Anonymous
Verified
08/07/2026
Esstenial for our days.
T
TONY PESTER
Verified
08/02/2026
Use with cardio helper to help regulate blood pressure.
S
Steve Cekalla
Verified
07/09/2026
An excellent choice for cardiovascular wellness and metabolism issues
T
TONY PESTER
Verified
03/20/2026
Repeat purchase.
A
Anonymous
03/02/2026
Leptinal is all important in giving us all the needed fats to our bodies.
I have used this product for over 20 years and I am 77 years old and I do not use any medications for cardiac support: no statins, my BP is normal, and no signs of cardiac problems.